dc.contributor.author
Absmeier, Eva
dc.contributor.author
Höpfler, Markus
dc.date.accessioned
2025-06-26T11:39:16Z
dc.date.available
2025-06-26T11:39:16Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/47992
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-47710
dc.description.abstract
mRNA decay is a key process controlling cellular protein levels and homeostasis. Cells tune mRNA stability by selective degradation, a process traditionally thought to rely on recognition of mRNA sequence features by proteins or complementary RNAs. By contrast, recent work showed how mRNA translation by the ribosome can direct selective mRNA decay. The ribosome reads out the codon composition and produces the nascent protein, both of which can be used to trigger decay via the CCR4-NOT complex.
en
dc.format.extent
3 Seiten
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject.ddc
500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften
dc.title
Der Richter und sein Henker: Boten-RNA-Abbau am Ribosom durch CCR4-NOT
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1007/s12268-025-2485-x
dcterms.bibliographicCitation.journaltitle
BIOspektrum
dcterms.bibliographicCitation.number
4
dcterms.bibliographicCitation.pagestart
367
dcterms.bibliographicCitation.pageend
369
dcterms.bibliographicCitation.volume
31
dcterms.bibliographicCitation.url
https://doi.org/10.1007/s12268-025-2485-x
refubium.affiliation
Biologie, Chemie, Pharmazie
refubium.affiliation.other
Institut für Chemie und Biochemie
refubium.funding
Springer Nature DEAL
refubium.note.author
Gefördert aus Open-Access-Mitteln der Freien Universität Berlin.
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.isPartOf.eissn
1868-6249
