dc.contributor.author
Elkilany, Aboelyazid
dc.contributor.author
Alwarraky, Mohamed
dc.contributor.author
Denecke, Timm
dc.contributor.author
Geisel, Dominik
dc.date.accessioned
2024-07-29T12:42:54Z
dc.date.available
2024-07-29T12:42:54Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/44330
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-44042
dc.description.abstract
For management of Budd-Chiari syndrome (BCS), a step-wise therapeutic approach starting with medical treatment, followed by endovascular recanalization, transjugular intrahepatic portosystemic shunt, and finally liver transplantation has been adopted. We retrospectively analyzed 51 patients with symptomatic short segment (<= 30 mm) hepatic vein (HV)-type BCS who underwent percutaneous transluminal balloon angioplasty (PTBA) with/without stenting to determine the feasibility, clinical effectiveness, and long-term outcomes. The intervention was technically successful in 94.1% of cases (48/51)-32 patients underwent PTBA and 16 patients underwent HV stenting. Procedure-related complications occurred in 14 patients (29.1%). The clinical success rate at 4 weeks was 91.7% (44/48). Nine patients underwent reintervention, six patients due to restenosis/occlusion and three patients with clinical failure. The mean primary patency duration was 64.6 +/- 19.9 months (CI, 58.5-70.8; range, 1.2-81.7 months). The cumulative 1-, 2-, and 5-year primary patency rates were 85.4, 74.5, and 58.3%, respectively. The cumulative 1-, 2-, and 5-year secondary patency rates were 93.8, 87.2, and 75%, respectively. The cumulative 1-, 2-, and 5-year survival rates were 97.9, 91.5, and 50%, respectively. Percutaneous transluminal angioplasty with and without stenting is effective and achieves excellent long-term patency and survival rates in patients with symptomatic HV-type BCS. With its lower incidence of re-occlusion and higher clinical success rate, HV angioplasty combined with stenting should be the preferred option especially in patients with segmental HV-type BCS.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Budd-Chiari-Syndrom
en
dc.subject
Percutane transluminale Ballonangioplastie
en
dc.subject
Long-Term Patency
en
dc.subject
Survival Rates
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Percutaneous transluminal angioplasty for symptomatic hepatic vein-type Budd-Chiari syndrome: feasibility and long-term outcomes
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
14095
dcterms.bibliographicCitation.doi
10.1038/s41598-022-16818-8
dcterms.bibliographicCitation.journaltitle
Scientific Reports
dcterms.bibliographicCitation.number
1
dcterms.bibliographicCitation.originalpublishername
Springer Nature
dcterms.bibliographicCitation.volume
12
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
Springer Nature DEAL
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
35982064
dcterms.isPartOf.eissn
2045-2322