dc.contributor.author
Kluge, Jennifer
dc.contributor.author
Bruggink, Robin
dc.contributor.author
Pandis, Nikolaos
dc.contributor.author
Unkovskiy, Alexey
dc.contributor.author
Jost-Brinkmann, Paul-Georg
dc.contributor.author
Kuijpers-Jagtman, Anne Marie
dc.contributor.author
Bartzela, Theodosia
dc.date.accessioned
2024-07-26T10:20:17Z
dc.date.available
2024-07-26T10:20:17Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/44317
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-44029
dc.description.abstract
This longitudinal study aimed to evaluate facial growth and soft tissue changes in infants with complete unilateral cleft lip, alveolus, and palate (CUCLAP) at ages 3, 9, and 12 months. Using 3D images of 22 CUCLAP infants, average faces and distance maps for the entire face and specific regions were created. Color-coded maps highlighted more significant soft tissue changes from 3 to 9 months than from 9 to 12 months. The first interval showed substantial growth in the entire face, particularly in the forehead, eyes, lower lip, chin, and cheeks (p < 0.001), while the second interval exhibited no significant growth. This study provides insights into facial soft tissue growth in CUCLAP infants during critical developmental stages, emphasizing substantial improvements between 3 and 9 months, mainly in the chin, lower lip, and forehead. However, uneven growth occurred in the upper lip, philtrum, and nostrils throughout both intervals, with an overall decline in growth from 9 to 12 months. These findings underscore the dynamic nature of soft tissue growth in CUCLAP patients, highlighting the need to consider these patterns in treatment planning. Future research should explore the underlying factors and develop customized treatment interventions for enhanced facial aesthetics and function in this population.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
stereophotogrammetry
en
dc.subject
three-dimensional
en
dc.subject
cleft lip and palate
en
dc.subject
facial growth
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Longitudinal Three-Dimensional Stereophotogrammetric Growth Analysis in Infants with Unilateral Cleft Lip and Palate from 3 to 12 Months of Age
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
6432
dcterms.bibliographicCitation.doi
10.3390/jcm12206432
dcterms.bibliographicCitation.journaltitle
Journal of Clinical Medicine
dcterms.bibliographicCitation.number
20
dcterms.bibliographicCitation.originalpublishername
MDPI AG
dcterms.bibliographicCitation.volume
12
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
37892569
dcterms.isPartOf.eissn
2077-0383