dc.contributor.author
Auer, Timo Alexander
dc.contributor.author
Collettini, Federico
dc.contributor.author
Segger, Laura
dc.contributor.author
Pelzer, Uwe
dc.contributor.author
Mohr, Raphael
dc.contributor.author
Krenzien, Felix
dc.contributor.author
Gebauer, Bernhard
dc.contributor.author
Geisel, Dominik
dc.contributor.author
Hosse, Clarissa
dc.contributor.author
Schöning, Wenzel
dc.contributor.author
Fehrenbach, Uli
dc.date.accessioned
2024-04-30T10:15:00Z
dc.date.available
2024-04-30T10:15:00Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/43399
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-43116
dc.description.abstract
cHCC-CCA is an uncommon type of liver cancer that exhibits clinical and pathological characteristics of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), which are the two main forms of primary liver cancer. The similarity to HCC and CCA makes therapeutical strategies challenging. The poor prognosis of CCA in general, as well as for cHCC-CCA, is mainly attributable to the fact that diagnosis is often at an advanced stage of disease. During the last decade, locoregional therapies usually performed by interventional radiologists and its established role in HCC treatment have gained an increasing role in CCA treatment as well. These comprise a wide range of options from tumor ablation procedures such as radiofrequency ablation (RFA), microwave ablation (MWA), computed tomography high-dose rate brachytherapy (CT-HDRBT), and cryoablation to transarterial chemoembolization (TACE), including the option of intra-arterial administration of radioactive spheres (transarterial radioembolization-TARE), and much attention has focused on the potential of individual concepts in recent years. The purpose of this review is to provide an overview of current radiologic interventions for CCA (excluding options for eCCA), to review and appraise the existing literature on the topic, and to provide an outlook on whether such interventions may have a role as treatment for cHCC-CCA in the future.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
combined hepatocellular-cholangiocarcinoma
en
dc.subject
cholangiocarcinoma
en
dc.subject
locoregional therapies
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Interventional Treatment Strategies in Intrahepatic Cholangiocarcinoma and Perspectives for Combined Hepatocellular-Cholangiocarcinoma
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
2655
dcterms.bibliographicCitation.doi
10.3390/cancers15092655
dcterms.bibliographicCitation.journaltitle
Cancers
dcterms.bibliographicCitation.number
9
dcterms.bibliographicCitation.originalpublishername
MDPI AG
dcterms.bibliographicCitation.volume
15
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
37174120
dcterms.isPartOf.eissn
2072-6694