dc.contributor.author
Becker, Luis
dc.contributor.author
Ziegeler, Katharina
dc.contributor.author
Diekhoff, Torsten
dc.contributor.author
Palmowski, Yannick
dc.contributor.author
Pumberger, Matthias
dc.contributor.author
Schömig, Friederike
dc.date.accessioned
2023-07-18T13:34:43Z
dc.date.available
2023-07-18T13:34:43Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/40159
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-39881
dc.description.abstract
Objective: Even though lumbosacral transitional vertebrae (LSTV) are one of the most common congenital anomalies of the spine, their effect on surrounding soft tissues is not well-studied. We therefore aimed at analyzing the association between LSTV and changes in volume, mass, symmetry, and degeneration of lumbar and trunk muscles.
Materials and methods: Abdomen-pelvis CT scans were analyzed in patients with LSTV and a matched control group. LSTV were classified according to the Castellvi classification. Muscles were segmented from the remaining soft tissue and their cross-sectional area and volume were examined at five defined levels. Threshold segmentation was used to differentiate between muscle fibers and fat tissue. Matched pairs were compared using Wilcoxon rank sum tests. For comparison of categorical data, chi-squared tests were performed and for associations between the degree of fusion and muscle size and degeneration, Spearman's correlation coefficients were calculated. Inter- and intrarater reliabilities were evaluated by computing intraclass correlation coefficients.
Results: Forty-six patients with LSTV and 46 controls were included. Muscle volume of the paraspinal and trunk muscles was significantly lower (707.0 cm(3) vs. 809.7 cm(3), p < 0.001) and fatty muscle changes were significantly increased in all but the caudal paravertebral muscles of LSTV patients (M. psoas p < 0.04, M. quadratus lumborum p < 0.001, paravertebral muscles p = 0.011, M. rectus abdominis p < 0.001, M. obliquus abdominis p < 0.001). Correlations between the degree of Castellvi classification and muscle volume were significant (p = 0.001).
Conclusion: LSTV are associated with a reduction in muscle volume and an increase in muscle degeneration of both lumbar and trunk muscles.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Transitional
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Musculature adaption in patients with lumbosacral transitional vertebrae: a matched-pair analysis of 46 patients
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1007/s00256-021-03722-x
dcterms.bibliographicCitation.journaltitle
Skeletal Radiology
dcterms.bibliographicCitation.number
8
dcterms.bibliographicCitation.originalpublishername
Springer Nature
dcterms.bibliographicCitation.pagestart
1697
dcterms.bibliographicCitation.pageend
1704
dcterms.bibliographicCitation.volume
50
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
Springer Nature DEAL
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
33533964
dcterms.isPartOf.issn
0364-2348
dcterms.isPartOf.eissn
1432-2161