dc.contributor.author
Thomale, Ulrich-Wilhelm
dc.contributor.author
Auer, C.
dc.contributor.author
Spennato, P.
dc.contributor.author
Schaumann, Andreas
dc.contributor.author
Behrens, P.
dc.contributor.author
Gorelyshev, S.
dc.contributor.author
Bogoslovskaia, E.
dc.contributor.author
Shulaev, A.
dc.contributor.author
Kabanian, A.
dc.contributor.author
Seliverstov, A.
dc.contributor.author
Alexeev, A.
dc.contributor.author
Ozgural, O.
dc.contributor.author
Kahilogullari, G.
dc.contributor.author
Schuhmann, M.
dc.contributor.author
Jimenez-Guerra, R.
dc.contributor.author
Wittayanakorn, N.
dc.contributor.author
Sukharev, A.
dc.contributor.author
Marquez-Rivas, J.
dc.contributor.author
Linsler, S.
dc.contributor.author
Damaty, A. El
dc.contributor.author
Vacek, P.
dc.contributor.author
Lovha, M.
dc.contributor.author
Guzman, R.
dc.contributor.author
Stricker, S.
dc.contributor.author
Beez, T.
dc.contributor.author
Wiegand, C.
dc.contributor.author
Azab, M.
dc.contributor.author
Buis, D.
dc.contributor.author
Sáez, M.
dc.contributor.author
Fleck, S.
dc.contributor.author
Dziugan, C.
dc.contributor.author
Ferreira, A.
dc.contributor.author
Radovnicky, T.
dc.contributor.author
Bührer, Christoph
dc.contributor.author
Lam, S.
dc.contributor.author
Sgouros, S.
dc.contributor.author
Roth, J.
dc.contributor.author
Constantini, S.
dc.contributor.author
Cavalheiro, S.
dc.contributor.author
Cinalli, G.
dc.contributor.author
Kulkarni, A. V.
dc.contributor.author
Bock, H. C.
dc.date.accessioned
2023-06-13T09:37:54Z
dc.date.available
2023-06-13T09:37:54Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/39810
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-39530
dc.description.abstract
Introduction: The TROPHY registry has been established to conduct an international multicenter prospective data collection on the surgical management of neonatal intraventricular hemorrhage (IVH)-related hydrocephalus to possibly contribute to future guidelines. The registry allows comparing the techniques established to treat hydrocephalus, such as external ventricular drainage (EVD), ventricular access device (VAD), ventricular subgaleal shunt (VSGS), and neuroendoscopic lavage (NEL). This first status report of the registry presents the results of the standard of care survey of participating centers assessed upon online registration.
Methods: On the standard of treatment forms, each center indicated the institutional protocol of interventions performed for neonatal post-hemorrhagic hydrocephalus (nPHH) for a time period of 2 years (Y1 and Y2) before starting the active participation in the registry. In addition, the amount of patients enrolled so far and allocated to a treatment approach are reported.
Results: According to the standard of treatment forms completed by 56 registered centers, fewer EVDs (Y1 55% Y2 46%) were used while more centers have implemented NEL (Y1 39%; Y2 52%) to treat nPHH. VAD (Y1 66%; Y2 66%) and VSGS (Y1 42%; Y2 41%) were used at a consistent rate during the 2 years. The majority of the centers used at least two different techniques to treat nPHH (43%), while 27% used only one technique, 21% used three, and 7% used even four different techniques. Patient data of 110 infants treated surgically between 9/2018 and 2/2021 (13% EVD, 15% VAD, 30% VSGS, and 43% NEL) were contributed by 29 centers.
Conclusions: Our results emphasize the varying strategies used for the treatment of nPHH. The international TROPHY registry has entered into a phase of growing patient recruitment. Further evaluation will be performed and published according to the registry protocol.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Infant hydrocephalus
en
dc.subject
Posthemorrhagic hydrocephalus
en
dc.subject
External ventricular drainage
en
dc.subject
Ventricular access device
en
dc.subject
Subgaleal shunt
en
dc.subject
Neuroendoscopic shunt
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
TROPHY registry — status report
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1007/s00381-021-05258-w
dcterms.bibliographicCitation.journaltitle
Child's Nervous System
dcterms.bibliographicCitation.originalpublishername
Springer Nature
dcterms.bibliographicCitation.pagestart
3549
dcterms.bibliographicCitation.pageend
3554
dcterms.bibliographicCitation.volume
37
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
Springer Nature DEAL
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
34184098
dcterms.isPartOf.issn
0256-7040
dcterms.isPartOf.eissn
1433-0350