dc.contributor.author
Kühnen, Peter
dc.contributor.author
Biebermann, Heike
dc.contributor.author
Wiegand, Susanna
dc.date.accessioned
2023-05-24T12:18:31Z
dc.date.available
2023-05-24T12:18:31Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/39532
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-39250
dc.description.abstract
Background: The increasing number of obese children and adolescence is a major problem in health-care systems. Currently, the gold standard for the treatment of these patients with obesity is a multicomponent lifestyle intervention. Unfortunately, this strategy is not leading to a substantial and long-lasting weight loss in the majority of patients. This is the reason why there is an urgent need to establish new treatment strategies for children and adolescents with obesity to reduce the risk for the development of any comorbidities like cardiovascular diseases or diabetes mellitus type 2. Summary: In this review, we outline available pharmacological therapeutic options for children and compare the available study data with the outcome of conservative treatment approaches. Key Messages: We discussed, in detail, how knowledge about underlying molecular mechanisms might support the identification of effective antiobesity drugs in the future and in which way this might modulate current treatment strategies to support children and adolescence with obesity to lose body weight.
en
dc.subject
Pharmacological treatment
en
dc.subject
Monogenic obesity
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Pharmacotherapy in Childhood Obesity
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1159/000518432
dcterms.bibliographicCitation.journaltitle
Hormone Research in Paediatrics
dcterms.bibliographicCitation.number
2
dcterms.bibliographicCitation.originalpublishername
Karger
dcterms.bibliographicCitation.pagestart
177
dcterms.bibliographicCitation.pageend
192
dcterms.bibliographicCitation.volume
95
dcterms.rightsHolder.note
Copyright applies in this work.
dcterms.rightsHolder.url
http://rightsstatements.org/vocab/InC/1.0/
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.note.author
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
de
refubium.note.author
This publication is shared with permission of the rights owner and made freely accessible through a DFG (German Research Foundation) funded license at either an alliance or national level.
en
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
34351307
dcterms.isPartOf.issn
1663-2818
dcterms.isPartOf.eissn
1663-2826