dc.contributor.author
Kreutzer, Kilian
dc.contributor.author
Steffen, Claudius
dc.contributor.author
Koerdt, Steffen
dc.contributor.author
Doll, Christian
dc.contributor.author
Ebker, Tobias
dc.contributor.author
Nahles, Susanne
dc.contributor.author
Flügge, Tabea
dc.contributor.author
Heiland, Max
dc.contributor.author
Beck-Broichsitter, Benedicta
dc.contributor.author
Rendenbach, Carsten
dc.date.accessioned
2022-08-26T11:57:09Z
dc.date.available
2022-08-26T11:57:09Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/36031
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-35746
dc.description.abstract
Background: This study was conducted to evaluate the feasibility, clinical outcomes, and accuracy of patient-specific 3D-printed miniplates for mandible reconstruction with fibula free flaps.
Methods: A feasibility study was conducted with 8 patients. Following virtual planning, patient-specific 1.0 mm titanium non-locking miniplates were produced via laser selective melting. 3D-printed cutting and drilling guides were used for segmental mandible resection and flap harvesting. Flap fixation was performed with two 4-hole miniplates and 2.0 mm non-locking screws (screw length 7 mm) for each intersegmental gap. Clinical follow-up was at least 6 months. Preoperative and postoperative CT/cone beam CT data were used for 3D accuracy analysis and evaluation of bone healing. Plate-related complications were monitored clinically.
Results: Patient-specific miniplate fixation of all flaps was successfully conducted (4 mono-segmental, 4 dual-segmental) with high accuracy (3.64 ± 1.18 mm) between the virtual plan and postoperative result. No technical complications were encountered intraoperatively. Osseous union occurred in all intersegmental gaps (1 partial, 18 complete) after 10 ± 2 months. No material fracture, dislocation, or plate exposure was observed.
Conclusions: Based on this pilot observational study including a limited number of patients, free flap fixation for mandibular reconstruction with patient-specific 3D-printed miniplates is feasible and associated with high accuracy, bone healing, and remote soft tissue complications.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
computer aided design/manufacture (CAD/CAM)
en
dc.subject
mandible reconstruction
en
dc.subject
fibula free flap
en
dc.subject
patient-specific
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Patient-Specific 3D-Printed Miniplates for Free Flap Fixation at the Mandible: A Feasibility Study
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
778371
dcterms.bibliographicCitation.doi
10.3389/fsurg.2022.778371
dcterms.bibliographicCitation.journaltitle
Frontiers in Surgery
dcterms.bibliographicCitation.originalpublishername
Frontiers Media SA
dcterms.bibliographicCitation.volume
9
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
35372463
dcterms.isPartOf.eissn
2296-875X