Title:
De Novo-Whole Genome Assembly of the Roborovski Dwarf Hamster (Phodopus roborovskii) Genome: An Animal Model for Severe/Critical COVID-19
Author(s):
Andreotti, Sandro; Altmüller, Janine; Quedenau, Claudia; Borodina, Tatiana; Nouailles, Geraldine; Teixeira Alves, Luiz Gustavo; Landthaler, Markus; Bieniara, Maximilian; Trimpert, Jakob; Wyler, Emanuel; Fraser, Bonnie
Year of publication:
2022
Available Date:
2022-08-04T08:25:48Z
Abstract:
The Roborovski dwarf hamster Phodopus roborovskii belongs to the Phodopus genus, one of the seven within Cricetinae subfamily. Like other rodents such as mice, rats, or ferrets, hamsters can be important animal models for a range of diseases. Whereas the Syrian hamster from the genus Mesocricetus is now widely used as a model for mild-to-moderate coronavirus disease 2019, Roborovski dwarf hamster shows a severe-to-lethal course of disease upon infection with the novel human coronavirus severe acute respiratory syndrome coronavirus 2.
Part of Identifier:
e-ISSN (online): 1759-6653
Keywords:
de novo
whole-genome assembly
Roborovski
dwarf
hamster
Phodopus roborovskii
DDC-Classification:
616 Krankheiten
Publication Type:
Wissenschaftlicher Artikel
URL of the Original Publication:
DOI of the Original Publication:
Journaltitle:
Genome Biology and Evolution
Publisher:
Oxford University Press
Department/institution:
Mathematik und Informatik
Veterinärmedizin
Institut für Informatik
Institut für Virologie
Comments:
Die Publikation wurde aus Open Access Publikationsgeldern der Freien Universität Berlin gefördert.
