dc.contributor.author
Feßler, Andrea T.
dc.contributor.author
Scholtzek, Anissa D.
dc.contributor.author
Schug, Angela R.
dc.contributor.author
Kohn, Barbara
dc.contributor.author
Weingart, Christiane
dc.contributor.author
Hanke, Dennis
dc.contributor.author
Schink, Anne-Kathrin
dc.contributor.author
Bethe, Astrid
dc.contributor.author
Lübke-Becker, Antina
dc.contributor.author
Schwarz, Stefan
dc.date.accessioned
2022-03-31T14:03:48Z
dc.date.available
2022-03-31T14:03:48Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/34540
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-34258
dc.description.abstract
A total of 215 isolates from infections of dogs and cats, including 49 Enterococcus faecalis, 37 Enterococcus faecium, 59 Escherichia coli, 56 Pseudomonas aeruginosa, and 14 Acinetobacter baumannii, were investigated for their susceptibility to 27 (Gram-positive bacteria) or 20 (Gram-negative bacteria) antimicrobial agents/combinations of antimicrobial agents by broth microdilution according to the recommendations of the Clinical and Laboratory Standards Institute. Moreover, all isolates were analysed for their susceptibility to the biocides benzalkonium chloride, chlorhexidine, polyhexanide, and octenidine by a recently published broth microdilution biocide susceptibility testing method. While the E. faecalis isolates did not show expanded resistances, considerable numbers of the E. faecium isolates were resistant to penicillins, macrolides, tetracyclines, and fluoroquinolones. Even a single vancomycin-resistant isolate that carried the vanA gene cluster was detected. Expanded multiresistance phenotypes were also detected among the E. coli isolates, including a single carbapenem-resistant, blaOXA-48-positive isolate. In addition, multiresistant A. baumannii isolates were detected. The minimal inhibitory concentrations of the biocides showed unimodal distributions but differed with respect to the biocide and the bacterial species investigated. Although there were no indications of a development of biocide resistance, some P. aeruginosa isolates exhibited benzalkonium MICs higher than the highest test concentration.
en
dc.format.extent
25 Seiten
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
P. aeruginosa
en
dc.subject
A. baumannii
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::616 Krankheiten
dc.subject.ddc
500 Naturwissenschaften und Mathematik::590 Tiere (Zoologie)::590 Tiere (Zoologie)
dc.title
Antimicrobial and Biocide Resistance among Canine and Feline Enterococcus faecalis, Enterococcus faecium, Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii Isolates from Diagnostic Submissions
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
152
dcterms.bibliographicCitation.doi
10.3390/antibiotics11020152
dcterms.bibliographicCitation.journaltitle
Antibiotics
dcterms.bibliographicCitation.number
2
dcterms.bibliographicCitation.originalpublishername
MDPI
dcterms.bibliographicCitation.volume
11
dcterms.bibliographicCitation.url
https://doi.org/10.3390/antibiotics11020152
refubium.affiliation
Veterinärmedizin
refubium.affiliation.other
Institut für Mikrobiologie und Tierseuchen
![Dieser Normdateneintrag wurde von einer Benutzerin oder einem Benutzer als gültig bestätigt.](/cache_202e45ad85b55efaeb29160f63cd3f3b/themes/FuCD/images/authority_control/invisible.gif)
refubium.affiliation.other
Tiermedizinisches Zentrum für Resistenzforschung (TZR)
refubium.affiliation.other
Klinik für Kleine Haustiere
![Dieser Normdateneintrag wurde von einer Benutzerin oder einem Benutzer als gültig bestätigt.](/cache_202e45ad85b55efaeb29160f63cd3f3b/themes/FuCD/images/authority_control/invisible.gif)
refubium.note.author
Die Publikation wurde aus Open Access Publikationsgeldern der Freien Universität Berlin gefördert.
de
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.isPartOf.eissn
2079-6382