dc.contributor.author
Kokolakis, Georgios
dc.contributor.author
Grawert, Leonie von
dc.contributor.author
Ulrich, Martina
dc.contributor.author
Lademann, Juergen
dc.contributor.author
Zuberbier, Torsten
dc.contributor.author
Hofmann, Maja A.
dc.date.accessioned
2022-03-02T14:30:25Z
dc.date.available
2022-03-02T14:30:25Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/34285
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-34003
dc.description.abstract
Background and Objectives:
Energy-based devices have been widely applied for skin ablation. A novel ablation technique based on thermomechanical principles (Tixel©) has been recently developed. The aim of this study was to examine the wound-healing process and clinical aspects after thermomechanical skin ablation.
Study Design/Materials and Methods:
Six female participants were treated with Tixel© on healthy skin of the dorsal side of the right forearm in a single session with a 600 µm protrusion and 12 milliseconds pulse. The treated area was examined with confocal laser scanning microscopy on day 1, 2, 7, and 14 after treatment. Clinical symptoms were evaluated at the same time-points.
Results:
All patients developed erythema and mild edema on the treated areas, which completely disappeared within 14 days. No post-inflammatory hyperpigmentation or scarring was observed. Thermomechanical skin ablation resulted in the formation of homogeneous micro-ablation zones. Two weeks after ablation, the honeycomb patterns of the epidermis in all examined layers was thoroughly restored. Thus, wound-healing was completed.
Conclusions:
Wound healing after thermomechanical skin ablation is much faster compared with other fractionated ablation methods. Treatment intervals of 2–4 weeks could be recommended.
en
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject
thermomechanical skin ablation
en
dc.subject
wound-healing
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Wound Healing Process After Thermomechanical Skin Ablation
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1002/lsm.23213
dcterms.bibliographicCitation.journaltitle
Lasers in Surgery and Medicine
dcterms.bibliographicCitation.number
8
dcterms.bibliographicCitation.originalpublishername
Wiley
dcterms.bibliographicCitation.pagestart
730
dcterms.bibliographicCitation.pageend
734
dcterms.bibliographicCitation.volume
52
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.funding
DEAL Wiley
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
31943275
dcterms.isPartOf.issn
0196-8092
dcterms.isPartOf.eissn
1096-9101