dc.contributor.author
Romanov, Georgy A.
dc.contributor.author
Schmülling, Thomas
dc.date.accessioned
2022-01-06T12:52:57Z
dc.date.available
2022-01-06T12:52:57Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/33365
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-33086
dc.description.abstract
Main conclusion
The free bases of cytokinins are the biologically active forms of the hormone while cytokinin ribosides become active only upon removal of the ribose residue.
Abstract
Cytokinins (CKs) belong to the classical plant hormones. They were discovered more than 65 years ago, but which molecular forms possess genuine CK activity is still matter of debate. Numerous studies support the view that only the free bases are the biologically active molecules. This standpoint has been challenged in a recent review (Nguyen et al. in Planta 254: 45, 2021) proposing that also CK ribosides may have genuine own CK activity. Here we critically discuss the pros and cons of this viewpoint considering the results of biological assays, CK binding studies, 3D structural data of CK-receptor interaction and mutant analyses. It is concluded that all types of study provide clear and convincing evidence only for biological activity of free bases and not ribosides; the latter are rather a transport form of the hormone without their own biological activity.
en
dc.format.extent
6 Seiten
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
3D protein structure
en
dc.subject
Cytokinin receptor
en
dc.subject
Cytokinin riboside
en
dc.subject
Cytokinin signaling
en
dc.subject
Plant hormone
en
dc.subject
Structure–activity relation
en
dc.subject.ddc
500 Naturwissenschaften und Mathematik::580 Pflanzen (Botanik)::580 Pflanzen (Botanik)
dc.title
On the biological activity of cytokinin free bases and their ribosides
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
27
dcterms.bibliographicCitation.doi
10.1007/s00425-021-03810-1
dcterms.bibliographicCitation.journaltitle
Planta
dcterms.bibliographicCitation.number
1
dcterms.bibliographicCitation.volume
255
dcterms.bibliographicCitation.url
https://doi.org/10.1007/s00425-021-03810-1
refubium.affiliation
Biologie, Chemie, Pharmazie
refubium.affiliation.other
Institut für Biologie / Dahlem Centre of Plant Sciences (DCPS)
refubium.funding
Springer Nature DEAL
refubium.note.author
Die Publikation wurde aus Open Access Publikationsgeldern der Freien Universität Berlin gefördert.
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.isPartOf.eissn
1432-2048
refubium.resourceType.provider
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