Title:
Automated glycan assembly of peptidoglycan backbone fragments
Author(s):
Dallabernardina, Pietro; Benazzi, Valentina; Laman, Jon D.; Seeberger, Peter H.; Loeffler, Felix F.
Year of publication:
2021
Available Date:
2021-12-07T09:04:32Z
Abstract:
We report the automated glycan assembly (AGA) of different oligosaccharide fragments of the bacterial peptidoglycan (PGN) backbone. Iterative addition on a solid support of an acetyl glucosamine and a new muramic acid building block is followed by cleavage from the solid support and final deprotection providing 10 oligosaccharides up to six units.
Part of Identifier:
e-ISSN (online): 1477-0539
Keywords:
automated glycan assembly
peptidoglycan backbone fragments
autoimmune disorders
DDC-Classification:
540 Chemie und zugeordnete Wissenschaften
Publication Type:
Wissenschaftlicher Artikel
URL of the Original Publication:
DOI of the Original Publication:
Journaltitle:
Organic & Biomolecular Chemistry
Department/institution:
Biologie, Chemie, Pharmazie
Institut für Chemie und Biochemie
