dc.contributor.author
Tschöpe, Carsten
dc.contributor.author
Alogna, Alessio
dc.contributor.author
Faragli, Alessandro
dc.contributor.author
Klingel, Karin
dc.contributor.author
Schmidt, Gunther
dc.contributor.author
Heilmann, Torsten Wolfgang
dc.contributor.author
Bastos, Marcelo B.
dc.contributor.author
Spillmann, Frank
dc.date.accessioned
2021-02-02T14:19:23Z
dc.date.available
2021-02-02T14:19:23Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/29458
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-29202
dc.description.abstract
Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is increasingly used in bi-ventricular failure with cardiogenic shock to maintain systemic perfusion. Nonetheless, it tends to increase left ventricular (LV) afterload and myocardial oxygen demand. In order to mitigate these negative effects on the myocardium, an Impella CP® (3.5 L/min Cardiac Output) can be used in conjunction with V-A ECMO (ECMELLA approach). We implemented this strategy in a patient with severe acute myocarditis complicated by cardiogenic shock. Due to a hemolysis crisis, Impella CP® had to be substituted with PulseCath iVAC2L®, which applies pulsatile flow to unload the LV. A subsequent improvement in LV systolic function was noted, with increased LV ejection fraction (LVEF), LV end-diastolic diameter (LVEDD) reduction, and a reduction in plasma free hemoglobin. This case documents the efficacy of iVAC2L in replacing Impella CP as a LV vent during V-A ECMO, with less hemolysis.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
mechanical circulatory support
en
dc.subject
mechanical unloading
en
dc.subject
heart failure
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Case Report First-in-Man Method Description: Left Ventricular Unloading With iVAC2L During Veno-Arterial Extracorporeal Membrane Oxygenation: From Veno-Arterial Extracorporeal Membrane Oxygenation to ECMELLA to EC-iVAC®
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
563448
dcterms.bibliographicCitation.doi
10.3389/fcvm.2020.563448
dcterms.bibliographicCitation.journaltitle
Frontiers in Cardiovascular Medicine
dcterms.bibliographicCitation.originalpublishername
Frontiers Media SA
dcterms.bibliographicCitation.volume
7
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
33102536
dcterms.isPartOf.eissn
2297-055X