dc.contributor.author
Rentzsch, Johannes
dc.contributor.author
Thoma, Lars
dc.contributor.author
Gaudlitz, Katharina
dc.contributor.author
Tänzer, Nicole
dc.contributor.author
Gallinat, Jürgen
dc.contributor.author
Kathmann, Norbert
dc.contributor.author
Ströhle, Andreas
dc.contributor.author
Plag, Jens
dc.date.accessioned
2020-10-19T10:14:43Z
dc.date.available
2020-10-19T10:14:43Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/28569
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-28318
dc.description.abstract
Panic disorder (PD) is associated with increased body vigilance and reduced cognitive resources directed at non-fear-related stimuli, particularly in the absence of stimulus-rich environments. To date, only few studies have investigated whether this deficit in PD is reflected in reduced mismatch negativity (MMN), an event-related potential indexing preattentive sensitivity to unexpected stimulus changes. We tested 35 patients affected by PD and 42 matched healthy controls in an oddball paradigm, using frequency and duration deviant stimuli to measure auditory MMN. PD patients displayed reduced duration MMN amplitudes in comparison to healthy controls. No group differences were detected for duration MMN latency, as well as frequency MMN indices. Results support the notion of reduced larly with regard to the preattentive processing of sound duration deviants. Additionally, our findings are in line with clinical studies reporting divergent deficits in preattentive processing of frequency and duration deviants.
en
dc.subject
Electroencephalography
en
dc.subject
Mismatch negativity
en
dc.subject
Preattentive information processing
en
dc.subject
Anxiety disorders
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Reduced Sensitivity to Non-Fear-Related Stimulus Changes in Panic Disorder
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.doi
10.1159/000498867
dcterms.bibliographicCitation.journaltitle
Neuropsychobiology
dcterms.bibliographicCitation.number
1
dcterms.bibliographicCitation.originalpublishername
Karger
dcterms.bibliographicCitation.pagestart
31
dcterms.bibliographicCitation.pageend
37
dcterms.bibliographicCitation.volume
78
dcterms.rightsHolder.note
Copyright applies in this work.
dcterms.rightsHolder.url
http://rightsstatements.org/vocab/InC/1.0/
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.note.author
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
de
refubium.note.author
This publication is shared with permission of the rights owner and made freely accessible through a DFG (German Research Foundation) funded license at either an alliance or national level.
en
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
30947222
dcterms.isPartOf.issn
0302-282X
dcterms.isPartOf.eissn
1423-0224