dc.contributor.author
Kadobianskyi, Mykola
dc.contributor.author
Schulze, Lisanne
dc.contributor.author
Schuelke, Markus
dc.contributor.author
Judkewitz, Benjamin
dc.date.accessioned
2019-10-30T09:26:27Z
dc.date.available
2019-10-30T09:26:27Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/25838
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-25599
dc.description.abstract
Studying neuronal circuits at cellular resolution is very challenging in vertebrates due to the size and optical turbidity of their brains. Danionella translucida, a close relative of zebrafish, was recently introduced as a model organism for investigating neural network interactions in adult individuals. Danionella remains transparent throughout its life, has the smallest known vertebrate brain and possesses a rich repertoire of complex behaviours. Here we sequenced, assembled and annotated the Danionella translucida genome employing a hybrid Illumina/Nanopore read library as well as RNA-seq of embryonic, larval and adult mRNA. We achieved high assembly continuity using low-coverage long-read data and annotated a large fraction of the transcriptome. This dataset will pave the way for molecular research and targeted genetic manipulation of this novel model organism.
en
dc.rights.uri
https://creativecommons.org/licenses/by/4.0/
dc.subject
Danionella translucida
en
dc.subject
Genomic sequencing libraries
en
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
dc.title
Hybrid genome assembly and annotation of Danionella translucida
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation.articlenumber
156
dcterms.bibliographicCitation.doi
10.1038/s41597-019-0161-z
dcterms.bibliographicCitation.journaltitle
Scientific Data
dcterms.bibliographicCitation.number
1
dcterms.bibliographicCitation.originalpublishername
Nature Publishing Group
dcterms.bibliographicCitation.volume
6
refubium.affiliation
Charité - Universitätsmedizin Berlin
refubium.resourceType.isindependentpub
no
dcterms.accessRights.openaire
open access
dcterms.bibliographicCitation.pmid
31451709
dcterms.isPartOf.eissn
2052-4463