Title:
VGLUT2 functions as a differentia marker for hippocampal output neurons
Author(s):
Wozny, Christian; Beed, Prateep; Nitzan, Noam; Pössnecker, Yona; Rost, Benjamin R.; Schmitz, Dietmar
Year of publication:
2018
Available Date:
2019-04-08T12:03:29Z
Abstract:
The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis.
Part of Identifier:
ISSN (print): 1662-5102
Keywords:
channelrhodopsin-2
entorhinal cortex
hippocampus
subiculum
synaptic transmission
VGLUT2
DDC-Classification:
610 Medizin und Gesundheit
Publication Type:
Wissenschaftlicher Artikel
DOI of the Original Publication:
PubMed ID of the Original Publication:
Journaltitle:
Frontiers in Cellular Neuroscience
Publisher:
Frontiers Media S.A.
Department/institution:
Charité - Universitätsmedizin Berlin