dc.contributor.author
Seibt, Julie
dc.contributor.author
Richard, Clement J.
dc.contributor.author
Sigl-Gloeckner, Johanna
dc.contributor.author
Takahashi, Naoya
dc.contributor.author
Kaplan, David I.
dc.contributor.author
Doron, Guy
dc.contributor.author
de Limoges, Denis
dc.contributor.author
Bocklisch, Christina
dc.contributor.author
Larkum, Matthew E.
dc.date.accessioned
2018-06-08T10:31:56Z
dc.date.available
2017-10-18T10:46:07.174Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/20597
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-23898
dc.description.abstract
How sleep influences brain plasticity is not known. In particular, why certain
electroencephalographic (EEG) rhythms are linked to memory consolidation is
poorly understood. Calcium activity in dendrites is known to be necessary for
structural plasticity changes, but this has never been carefully examined
during sleep. Here, we report that calcium activity in populations of
neocortical dendrites is increased and synchronised during oscillations in the
spindle range in naturally sleeping rodents. Remarkably, the same relationship
is not found in cell bodies of the same neurons and throughout the cortical
column. Spindles during sleep have been suggested to be important for brain
development and plasticity. Our results provide evidence for a physiological
link of spindles in the cortex specific to dendrites, the main site of
synaptic plasticity.
en
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
Cellular neuroscience
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
dc.title
Cortical dendritic activity correlates with spindle-rich oscillations during
sleep in rodents
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Nature Communications. - 8 (2017), Artikel Nr. 684
dcterms.bibliographicCitation.doi
10.1038/s41467-017-00735-w
dcterms.bibliographicCitation.url
http://www.nature.com/articles/s41467-017-00735-w
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000028338
refubium.note.author
Der Artikel wurde in einer reinen Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000009008
dcterms.accessRights.openaire
open access