dc.contributor.author
Paßlack, Nadine
dc.contributor.author
Mainzer, Barbara
dc.contributor.author
Lahrssen-Wiederholt, Monika
dc.contributor.author
Schafft, Helmut
dc.contributor.author
Palavinskas, Richard
dc.contributor.author
Breithaupt, Angele
dc.contributor.author
Zentek, Jürgen
dc.date.accessioned
2018-06-08T03:49:21Z
dc.date.available
2015-04-23T09:55:40.631Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/15999
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-20185
dc.description.abstract
This study was conducted to measure the concentrations of strontium (Sr),
barium (Ba), cadmium (Cd), copper (Cu), zinc (Zn), manganese (Mn), chromium
(Cr), antimony (Sb), selenium (Se), and lead (Pb) in canine liver, renal
cortex, and renal medulla, and the association of these concentrations with
age, gender, and occurrence of chronic kidney disease (CKD). Tissues from 50
dogs were analyzed using inductively coupled plasma mass spectrometry. Cu, Zn,
and Mn levels were highest in the liver followed by the renal cortex and renal
medulla. The highest Sr, Cd, and Se concentrations were measured in the renal
cortex while lower levels were found in the renal medulla and liver. Female
dogs had higher tissue concentrations of Sr (liver and renal medulla), Cd
(liver), Zn (liver and renal cortex), Cr (liver, renal cortex, and renal
medulla), and Pb (liver) than male animals. Except for Mn and Sb, age-
dependent variations were observed for all element concentrations in the
canine tissues. Hepatic Cd and Cr concentrations were higher in dogs with CKD.
In conclusion, the present results provide new knowledge about the storage of
specific elements in canine liver and kidneys, and can be considered important
reference data for diagnostic methods and further investigations.
en
dc.rights.uri
http://creativecommons.org/licenses/by-nc/3.0/
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft
dc.title
Concentrations of strontium, barium, cadmium, copper, zinc, manganese,
chromium, antimony, selenium, and lead in the liver and kidneys of dogs
according to age, gender, and the occurrence of chronic kidney disease
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Journal of Veterinary Science. - 16 (2015), 1, S. 57-66
dc.identifier.sepid
43463
dcterms.bibliographicCitation.doi
10.4142/jvs.2015.16.1.57
dcterms.bibliographicCitation.url
http://dx.doi.org/10.4142/jvs.2015.16.1.57
refubium.affiliation
Veterinärmedizin
de
refubium.funding
Deutsche Forschungsgemeinschaft (DFG)
refubium.mycore.fudocsId
FUDOCS_document_000000022272
refubium.note.author
Gefördert durch die DFG und den Open Access Publikationsfonds der Freien
Universität Berlin
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000004809
dcterms.accessRights.openaire
open access