dc.contributor.author
Megges, Matthias
dc.contributor.author
Geissler, Sven
dc.contributor.author
Duda, Georg N.
dc.contributor.author
Adjaye, James
dc.date.accessioned
2018-06-08T03:43:29Z
dc.date.available
2016-03-07T11:58:44.052Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/15796
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-19983
dc.description.abstract
An induced pluripotent stem cell line was generated from primary human bone
marrow derived mesenchymal stromal cells of a 74 year old donor using
retroviruses harboring OCT4, SOX2, KLF4 and c-MYC in combination with the
following inhibitors TGFβ receptor-SB 431542, MEK-PD325901, and p53-Pifithrin
α. Pluripotency was confirmed both in vitro and in vivo.
en
dc.rights.uri
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc
500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
dc.title
Generation of an iPS cell line from bone marrow derived mesenchymal stromal
cells from an elderly patient
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Stem Cell Research. - 15 (2015), 3, S. 565-568
dcterms.bibliographicCitation.doi
10.1016/j.scr.2015.10.003
dcterms.bibliographicCitation.url
http://www.sciencedirect.com/science/article/pii/S1873506115001385
refubium.affiliation
Biologie, Chemie, Pharmazie
de
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000024092
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000006077
dcterms.accessRights.openaire
open access