dc.contributor.author
Schnapauff, D.
dc.contributor.author
Collettini, F.
dc.contributor.author
Steffen, I.
dc.contributor.author
Wieners, G.
dc.contributor.author
Hamm, B.
dc.contributor.author
Gebauer, B.
dc.contributor.author
Maurer, M. H.
dc.date.accessioned
2018-06-08T03:36:49Z
dc.date.available
2016-04-04T09:43:24.637Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/15565
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-19753
dc.description.abstract
Purpose To analyse and compare the costs of hepatic tumor ablation with
computed tomography (CT)-guided high-dose rate brachytherapy (CT-HDRBT) and
CT-guided radiofrequency ablation (CT-RFA) as two alternative minimally
invasive treatment options of hepatocellular carcinoma (HCC). Materials and
methods An activity based process model was created determining working steps
and required staff of CT-RFA and CT-HDRBT. Prorated costs of equipment use
(purchase, depreciation, and maintenance), costs of staff, and expenditure for
disposables were identified in a sample of 20 patients (10 treated by CT-RFA
and 10 by CT-HDRBT) and compared. A sensitivity and break even analysis was
performed to analyse the dependence of costs on the number of patients treated
annually with both methods. Results Costs of CT-RFA were nearly stable with
mean overall costs of approximately 1909 €, 1847 €, 1816 € and 1801 € per
patient when treating 25, 50, 100 or 200 patients annually, as the main factor
influencing the costs of this procedure was the single-use RFA probe. Mean
costs of CT-HDRBT decreased significantly per patient ablation with a rising
number of patients treated annually, with prorated costs of 3442 €, 1962 €,
1222 € and 852 € when treating 25, 50, 100 or 200 patients, due to low costs
of single-use disposables compared to high annual fix-costs which
proportionally decreased per patient with a higher number of patients treated
annually. A break-even between both methods was reached when treating at least
55 patients annually. Conclusion Although CT-HDRBT is a more complex procedure
with more staff involved, it can be performed at lower costs per patient from
the perspective of the medical provider when treating more than 55 patients
compared to CT-RFA, mainly due to lower costs for disposables and a decreasing
percentage of fixed costs with an increasing number of treatments.
en
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
High-dose rate brachytherapy
dc.subject
Radiofrequency ablation
dc.subject
Minimally invasive treatment
dc.subject.ddc
600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
dc.title
Activity-based cost analysis of hepatic tumor ablation using CT-guided high-
dose rate brachytherapy or CT-guided radiofrequency ablation in hepatocellular
carcinoma
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Radiation Oncology. - 11 (2016), Artikel Nr. 26
dcterms.bibliographicCitation.doi
10.1186/s13014-016-0606-x
dcterms.bibliographicCitation.url
http://ro-journal.biomedcentral.com/articles/10.1186/s13014-016-0606-x
refubium.affiliation
Charité - Universitätsmedizin Berlin
de
refubium.mycore.fudocsId
FUDOCS_document_000000024314
refubium.note.author
Der Artikel wurde in einer Open-Access-Zeitschrift publiziert.
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000006228
dcterms.accessRights.openaire
open access