dc.contributor.author
Voigt, Kathrin
dc.contributor.author
Rademacher, Eva
dc.date.accessioned
2018-06-08T03:31:22Z
dc.date.available
2016-04-01T08:49:10.208Z
dc.identifier.uri
https://refubium.fu-berlin.de/handle/fub188/15365
dc.identifier.uri
http://dx.doi.org/10.17169/refubium-19553
dc.description.abstract
The value of propolis as a disinfectant agent in the bee hive is considerable.
We investigated the fungistatic effect of cinnamic acid and pinocembrin on the
pathogen Ascosphaera apis causing chalkbrood disease in bee colonies in the
laboratory with an agar diffusion test on malt extract agar. The minimal
fungicide inhibitory concentration was 0.5% for cinnamic acid and 1.5% for
pinocembrin (MIC -values). Both substances were tested by individual
application for adult bee tolerance in a range of dosages and for brood
tolerance (L1 - L5) referring to the MIC values. The dermal toxicity of adult
bees for cinnamic acid and pinocembrin was low, a maximum of 3.3% even in the
highest dosage of 1000 μg (concentration 20%) and 250 μg (concentration 5%)
per bee, respectively. The mortality rates showed no significant differences
to the controls (z-test, p≤0.05). First results on brood tolerability after
application of test substances resulted in larval mortality but primarily in
the group of young larvae. The mortality reduced simultaneous with the
increasing larval weight. The total larval mortality 72 hours after the
application over all stages was 28.7% for cinnamic acid and 13.1% for
pinocembrin (positive control group 24.8%; negative control group 15.4%). The
test groups showed no significant increased mortality compared to the control
groups (z-test, p≥0.05). Both substances have in vitro fungicide potential and
can be considered as potential active agents against A. apis in honey bee
drugs. The results provide high tolerance of adult bees and an indication for
larval tolerability most notably in elder larvae.
en
dc.rights.uri
http://creativecommons.org/licenses/by-nc-nd/3.0/
dc.subject
Apis mellifera
dc.subject
Ascosphaera apis
dc.subject.ddc
500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie
dc.title
Effect of the Propolis Components, Cinnamic Acid and Pinocembrin, on Apis
Mellifera and Ascosphaera Apis
dc.type
Wissenschaftlicher Artikel
dcterms.bibliographicCitation
Journal of Apicultural Science. - 59 (2015), 1, S. 89-95
dcterms.bibliographicCitation.doi
10.1515/jas-2015-0010
dcterms.bibliographicCitation.url
http://www.degruyter.com/view/j/jas.2015.59.issue-1/jas-2015-0010/jas-2015-0010.xml
refubium.affiliation
Biologie, Chemie, Pharmazie
de
refubium.mycore.fudocsId
FUDOCS_document_000000024300
refubium.resourceType.isindependentpub
no
refubium.mycore.derivateId
FUDOCS_derivate_000000006215
dcterms.accessRights.openaire
open access