Title:
Enabling Technologies in Carbohydrate Chemistry: Automated Glycan Assembly, Flow Chemistry and Data Science
Author(s):
Lin, Mei‐Huei; Wolf, Jakob B.; Sletten, Eric T.; Cambié, Dario; Danglad-Flores, José; Seeberger, Peter H.
Year of publication:
2023
Available Date:
2023-04-20T07:00:18Z
Abstract:
The synthesis of defined oligosaccharides is a complex task. Several enabling technologies have been introduced in the last two decades to facilitate synthetic access to these valuable biomolecules. In this concept, we describe the technological solutions that have advanced glycochemistry using automated glycan assembly, flow chemistry and data science as examples. We highlight how the synergies between these different technologies can further advance the field, with progress toward the realization of a self‐driving lab for glycan synthesis.
Part of Identifier:
e-ISSN (online): 1439-7633
Keywords:
carbohydrates
flow chemistry
glycosylation
oligosaccharides
reaction automation
DDC-Classification:
540 Chemie und zugeordnete Wissenschaften
Publication Type:
Wissenschaftlicher Artikel
URL of the Original Publication:
DOI of the Original Publication:
Journaltitle:
ChemBioChem
Department/institution:
Biologie, Chemie, Pharmazie
Institut für Chemie und Biochemie