Haupttitel:
VGLUT2 functions as a differentia marker for hippocampal output neurons
Autor*in:
Wozny, Christian; Beed, Prateep; Nitzan, Noam; Pössnecker, Yona; Rost, Benjamin R.; Schmitz, Dietmar
Datum der Freigabe:
2019-04-08T12:03:29Z
Abstract:
The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis.
Teil des Identifiers:
ISSN (print): 1662-5102
Freie Schlagwörter:
channelrhodopsin-2
entorhinal cortex
hippocampus
subiculum
synaptic transmission
VGLUT2
DDC-Klassifikation:
610 Medizin und Gesundheit
Publikationstyp:
Wissenschaftlicher Artikel
PubMed ID der Originalausgabe:
Zeitschrift:
Frontiers in Cellular Neuroscience
Verlag:
Frontiers Media S.A.
Fachbereich/Einrichtung:
Charité - Universitätsmedizin Berlin