id,collection,dc.contributor.author,dc.date.accessioned,dc.date.available,dc.date.issued,dc.description.abstract[en],dc.format.extent,dc.identifier.uri,dc.language,dc.rights.uri,dc.subject,dc.subject.ddc,dc.title,dc.type,dcterms.accessRights.openaire,dcterms.bibliographicCitation,dcterms.bibliographicCitation.doi,dcterms.bibliographicCitation.url,refubium.affiliation[de],refubium.mycore.derivateId,refubium.mycore.fudocsId,refubium.note.author,refubium.resourceType.isindependentpub "16981f8c-a0c5-4706-8bb3-e31430a4d91f","fub188/15","Meinke, Martina C.||Nowbary, Ceylan K.||Schanzer, Sabine||Vollert, Henning||Lademann, Juergen||Darvin, Maxim E.","2018-06-08T10:55:45Z","2017-09-15T08:53:29.029Z","2017","Two differently designed, spatially resolved reflectance spectroscopy-based scanners and two-photon tomography were used for noninvasive in vivo determination of cutaneous carotenoids, and collagen I/elastin aging index of dermis, respectively, in the skin of 29 healthy female volunteers between 40 and 56 years of age. The volunteers received a supplement in the form of a carotenoid-rich natural curly kale extract containing 1650 µg of carotenoids in total (three capsules of 550 µg), once a day. Measurements were taken before, after 5 months and after 10 months of daily supplementation. The results showed significantly increased values for the cutaneous carotenoids and the collagen I/elastin aging index of dermis 5 and 10 months after the beginning of the study. The obtained results show that a natural carotenoid- rich extract could prevent the aging-related collagen I degradation in the dermis and improve the extracellular matrix.","10 S.","https://refubium.fu-berlin.de/handle/fub188/21347||http://dx.doi.org/10.17169/refubium-24642","eng","http://creativecommons.org/licenses/by/4.0/","skin aging||two photon tomography||reflectance spectroscopy||noninvasive methods||auto fluorescence||second harmonic generation||nutrition","600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit","Influences of Orally Taken Carotenoid-Rich Curly Kale Extract on Collagen I/Elastin Index of the Skin","Wissenschaftlicher Artikel","open access","Nutrients. - 9 (2017), 7, Artikel Nr. 775","10.3390/nu9070775","http://www.mdpi.com/2072-6643/9/7/775","Charité - Universitätsmedizin Berlin","FUDOCS_derivate_000000008747","FUDOCS_document_000000027973","Der Artikel wurde in einer reinen Open-Access-Zeitschrift publiziert.","no"